Tracing exogenous surfactant in vivo in rabbits by the natural variation of 13C

Tracing exogenous surfactant in vivo in rabbits by the natural variation of 13C

Abstract Background Respiratory Distress Syndrome (RDS) is a prematurity-related breathing disorder caused by a quantitative deficiency of pulmonary surfactant. Surfactant replacement therapy is effective for RDS newborns, although treatment failure has been reported. The aim of this study is to tra...

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Bibliographic Details
Main Authors: Sonia Giambelluca, Francesca Ricci, Manuela Simonato, Luca Vedovelli, Umberto Traldi, Alessio Correani, Costanza Casiraghi, Matteo Storti, Arianna Mersanne, Paola Cogo, Fabrizio Salomone, Virgilio P. Carnielli
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Respiratory Research
Subjects:
Respiratory distress syndrome
Lung surfactant
Surfactant replacement therapy
13C natural abundance
Stable isotope
Online Access:http://link.springer.com/article/10.1186/s12931-019-1124-9

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http://link.springer.com/article/10.1186/s12931-019-1124-9

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