Real-time electrochemical recording of dopamine release under optogenetic stimulation.

Dopaminergic PC12 cells can synthesize and release dopamine, providing a good cellular model for investigating dopamine regulation. Optogenetic stimulation of channelrhodopsin-2 provides high spatial and temporal precision for selective stimulation as a powerful neuromodulation tool for neuroscience...

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Bibliographic Details
Main Authors: Wen-Tai Chiu, Che-Ming Lin, Tien-Chun Tsai, Chun-Wei Wu, Ching-Lin Tsai, Sheng-Hsiang Lin, Jia-Jin Jason Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3930700?pdf=render