Shigella dysenteriae modulates BMP pathway to induce mucin gene expression in vivo and in vitro.

Mucosal epithelial cells in the intestine act as the first line of host defense against pathogens by increasing mucin production for clearance. Despite this fact, the underlying molecular mechanisms by which Shigella dysenteriae transduce mucin gene expression remain poorly defined. The goal of this...

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Bibliographic Details
Main Authors: Ashidha Gopal, Soumya Chidambaram Iyer, Udhayakumar Gopal, Niranjali Devaraj, Devaraj Halagowder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4218725?pdf=render