Discerning the ancestry of European Americans in genetic association studies.

European Americans are often treated as a homogeneous group, but in fact form a structured population due to historical immigration of diverse source populations. Discerning the ancestry of European Americans genotyped in association studies is important in order to prevent false-positive or false-n...

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Bibliographic Details
Main Authors: Alkes L Price, Johannah Butler, Nick Patterson, Cristian Capelli, Vincenzo L Pascali, Francesca Scarnicci, Andres Ruiz-Linares, Leif Groop, Angelica A Saetta, Penelope Korkolopoulou, Uri Seligsohn, Alicja Waliszewska, Christine Schirmer, Kristin Ardlie, Alexis Ramos, James Nemesh, Lori Arbeitman, David B Goldstein, David Reich, Joel N Hirschhorn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2211542?pdf=render