Functional transcriptomics of wild-caught Lutzomyia intermedia salivary glands: identification of a protective salivary protein against Leishmania braziliensis infection.

BACKGROUND: Leishmania parasites are transmitted in the presence of sand fly saliva. Together with the parasite, the sand fly injects salivary components that change the environment at the feeding site. Mice immunized with Phlebotomus papatasi salivary gland (SG) homogenate are protected against Lei...

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Main Authors: Tatiana R de Moura, Fabiano Oliveira, Marcia W Carneiro, José Carlos Miranda, Jorge Clarêncio, Manoel Barral-Netto, Cláudia Brodskyn, Aldina Barral, José M C Ribeiro, Jesus G Valenzuela, Camila I de Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3662654?pdf=render