Prediction of amyloidogenic and disordered regions in protein chains.

The determination of factors that influence protein conformational changes is very important for the identification of potentially amyloidogenic and disordered regions in polypeptide chains. In our work we introduce a new parameter, mean packing density, to detect both amyloidogenic and disordered r...

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Bibliographic Details
Main Authors: Oxana V Galzitskaya, Sergiy O Garbuzynskiy, Michail Yurievich Lobanov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0020177