IPSE, a urogenital parasite-derived immunomodulatory molecule, suppresses bladder pathogenesis and anti-microbial peptide gene expression in bacterial urinary tract infection

IPSE, a urogenital parasite-derived immunomodulatory molecule, suppresses bladder pathogenesis and anti-microbial peptide gene expression in bacterial urinary tract infection

Abstract Background Parasitic infections can increase susceptibility to bacterial co-infections. This may be true for urogenital schistosomiasis and bacterial urinary tract co-infections (UTI). We previously reported that this co-infection is facilitated by S. haematobium eggs triggering interleukin...

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Bibliographic Details
Main Authors: Evaristus C. Mbanefo, Loc Le, Luke F. Pennington, Yi- Ju Hsieh, Justin I. Odegaard, Kristina Lapira, Theodore S. Jardetzky, Franco H. Falcone, Michael H. Hsieh
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Parasites & Vectors
Subjects:
Schistosome
Schistosoma
Haematobium
IPSE
α-1
Bladder
Online Access:https://doi.org/10.1186/s13071-020-04490-8

Internet

https://doi.org/10.1186/s13071-020-04490-8

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