Targeting serum glucocorticoid-regulated kinase-1 in squamous cell carcinoma of the head and neck: a novel modality of local control.

PURPOSE:The inhibition of serum glucocorticoid-regulated kinase-1 (SGK-1) has been found to decrease growth of colon and prostate cancer cells. The purpose of this study is to evaluate the therapeutic effect of SGK-1 inhibition in head and neck squamous cell carcinoma (SCC). EXPERIMENTAL DESIGN:Huma...

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Bibliographic Details
Main Authors: Henrik O Berdel, Hongyu Yin, Jun Yao Liu, Karolina Grochowska, Christopher Middleton, Nathan Yanasak, Rafik Abdelsayed, Wolfgang E Berdel, Mahmood Mozaffari, Jack C Yu, Babak Baban
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4259465?pdf=render