Antibody affinity versus dengue morphology influences neutralization.

Antibody affinity versus dengue morphology influences neutralization.

Different strains within a dengue serotype (DENV1-4) can have smooth, or "bumpy" surface morphologies with different antigenic characteristics at average body temperature (37°C). We determined the neutralizing properties of a serotype cross-reactive human monoclonal antibody (HMAb) 1C19 fo...

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Bibliographic Details
Main Authors: Guntur Fibriansah, Elisa X Y Lim, Jan K Marzinek, Thiam-Seng Ng, Joanne L Tan, Roland G Huber, Xin-Ni Lim, Valerie S Y Chew, Victor A Kostyuchenko, Jian Shi, Ganesh S Anand, Peter J Bond, James E Crowe, Shee-Mei Lok
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009331

Internet

https://doi.org/10.1371/journal.ppat.1009331

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