SCRaMbLE generates evolved yeasts with increased alkali tolerance

Abstract Background Strains with increased alkali tolerance have a broad application in industrial, especially for bioremediation, biodegradation, biocontrol and production of bio-based chemicals. A novel synthetic chromosome recombination and modification by LoxP-mediated evolution (SCRaMbLE) syste...

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Bibliographic Details
Main Authors: Lu Ma, Yunxiang Li, Xinyu Chen, Mingzhu Ding, Yi Wu, Ying-Jin Yuan
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-019-1102-4