Asymmetric Titanium-Catalyzed Cyclopropanation of Nitriles with Grignard Reagents

Abstract The titanium-catalyzed asymmetric cyclopropanation of cyanoesters­ with Grignard reagents was investigated for the first time. Particularly, the study of the efficiency of Taddol-based titanium complexes­ has shown that the prior preparation of Taddol titanium complexes was not required and...

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Bibliographic Details
Main Authors: Julien Caillé, Paul Setzer, Fabien Boeda, Morwenna S. M. Pearson-Long, Philippe Bertus
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2018-01-01
Series:SynOpen
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1591933