ABCA1 contributes to macrophage deposition of extracellular cholesterol

ABCA1 contributes to macrophage deposition of extracellular cholesterol

We previously reported that cholesterol-enriched macrophages excrete cholesterol into the extracellular matrix. A monoclonal antibody that detects cholesterol microdomains labels the deposited extracellular particles. Macro­phage deposition of extracellular cholesterol depends, in part, on ABCG1, an...

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Bibliographic Details
Main Authors: Xueting Jin, Sebastian R. Freeman, Boris Vaisman, Ying Liu, Janet Chang, Neta Varsano, Lia Addadi, Alan Remaley, Howard S. Kruth
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
apolipoprotein A-I
high density lipoprotein
probucol
TO901317
ATP binding cassette transporter A1
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520355012

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http://www.sciencedirect.com/science/article/pii/S0022227520355012

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