Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif
<p>Abstract</p> <p>Background</p> <p>The interactions between PDZ (PSD-95, Dlg, ZO-1) domains and PDZ-binding motifs play central roles in signal transductions within cells. Proteins with PDZ domains bind to PDZ-binding motifs almost exclusively when the motifs are loca...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-06-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/12/300 |