Attenuated LKB1-SIK1 signaling promotes epithelial-mesenchymal transition and radioresistance of non–small cell lung cancer cells

Attenuated LKB1-SIK1 signaling promotes epithelial-mesenchymal transition and radioresistance of non–small cell lung cancer cells

Abstract Background Radiotherapy is one of the main therapeutic approaches for non–small cell lung cancer (NSCLC). However, radioresistant cancer cells can eventually cause tumor relapse and even fatal metastasis. It is thought that radioresistance and metastasis could be potentially linked by epith...

Full description

Bibliographic Details
Main Authors: Yuan-Hu Yao, Yan Cui, Xiang-Nan Qiu, Long-Zhen Zhang, Wei Zhang, Hao Li, Jin-Ming Yu
Format: Article
Language:English
Published: BMC 2016-06-01
Series:Chinese Journal of Cancer
Subjects:
Radioresistance
Lung cancer
Metastasis
Epithelial-mesenchymal transition
LKB1
SIK1
Online Access:http://link.springer.com/article/10.1186/s40880-016-0113-3

Internet

http://link.springer.com/article/10.1186/s40880-016-0113-3

Similar Items