Role of Aryl Hydrocarbon Receptor (AhR) in the Regulation of Immunity and Immunopathology During Trypanosoma cruzi Infection

Role of Aryl Hydrocarbon Receptor (AhR) in the Regulation of Immunity and Immunopathology During Trypanosoma cruzi Infection

Resistance to Trypanosoma cruzi infection is dependent on a rapid induction of Th1-type and CD8+ T cell responses that should be promptly balanced to prevent immunopathology. T. cruzi-infected B6 mice are able to control parasite replication but show a limited expansion of Foxp3+regulatory T (Treg)...

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Bibliographic Details
Main Authors: Laura Fernanda Ambrosio, Constanza Insfran, Ximena Volpini, Eva Acosta Rodriguez, Horacio Marcelo Serra, Francisco J. Quintana, Laura Cervi, Claudia Cristina Motrán
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
Chagas disease
TCDD
ITE
regulatory T cells
AhR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00631/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00631/full

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