Direct activation of human dendritic cells by particle-bound but not soluble MHC class II ligand.

Dendritic cells (DCs) are key activators of cellular immune responses through their capacity to induce naïve T cells and sustained effector T cell responses. This capacity is a function of their superior efficiency of antigen presentation via MHC class I and class II molecules, and the expression of...

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Bibliographic Details
Main Authors: Renato B Baleeiro, Karl-Heinz Wiesmüller, Lars Dähne, Jürgen Lademann, José A Barbuto, Peter Walden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3642081?pdf=render