Haplotypes in the complement factor H (CFH) gene: associations with drusen and advanced age-related macular degeneration.

Age-related macular degeneration (AMD), the leading cause of blindness in the Western world, is a complex disease that affects people over 50 years old. The complement factor H (CFH) gene has been repeatedly shown to be a major factor in determining susceptibility to the advanced form of the conditi...

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Bibliographic Details
Main Authors: Peter J Francis, Dennis W Schultz, Sara Hamon, Jurg Ott, Richard G Weleber, Michael L Klein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2077927?pdf=render