Therapeutic Effect of BDNF-Overexpressing Human Neural Stem Cells (F3.BDNF) in a Contusion Model of Spinal Cord Injury in Rats

Therapeutic Effect of BDNF-Overexpressing Human Neural Stem Cells (F3.BDNF) in a Contusion Model of Spinal Cord Injury in Rats

The most common type of spinal cord injury is the contusion of the spinal cord, which causes progressive secondary tissue degeneration. In this study, we applied genetically modified human neural stem cells overexpressing BDNF (brain-derived neurotrophic factor) (F3.BDNF) to determine whether they c...

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Bibliographic Details
Main Authors: Da-Jeong Chang, Hwi-Young Cho, Seyoung Hwang, Nayeon Lee, Chunggab Choi, Hyunseung Lee, Kwan Soo Hong, Seung-Hun Oh, Hyun Sook Kim, Dong Ah Shin, Young Wook Yoon, Jihwan Song
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
spinal cord injury
contusion
neural stem cells
brain-derived neurotrophic factor (BDNF)
functional recovery
Online Access:https://www.mdpi.com/1422-0067/22/13/6970

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https://www.mdpi.com/1422-0067/22/13/6970

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