Sequential Immunization With Heterologous Viruses Does Not Result in Attrition of the B Cell Memory in Rainbow Trout

Sequential Immunization With Heterologous Viruses Does Not Result in Attrition of the B Cell Memory in Rainbow Trout

Long-term immunity is of great importance for protection against pathogens and has been extensively studied in mammals. Successive heterologous infections can affect the maintenance of immune memory, inducing attrition of T memory cells and diminishing B cell mediated protection. In fish, the basis...

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Bibliographic Details
Main Authors: Sofie Navelsaker, Susana Magadan, Luc Jouneau, Edwige Quillet, Niels J. Olesen, Hetron Mweemba Munang'andu, Pierre Boudinot, Øystein Evensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
antibodies
B cell repertoire
heterologous immunization
public response
fish immunology
RepSeq
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02687/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02687/full

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