Different Perivascular Space Burdens in Idiopathic Rapid Eye Movement Sleep Behavior Disorder and Parkinson’s Disease

Different Perivascular Space Burdens in Idiopathic Rapid Eye Movement Sleep Behavior Disorder and Parkinson’s Disease

BackgroundExcessive aggregation of α-synuclein is the key pathophysiological feature of Parkinson’s disease (PD). Rapid eye movement sleep behavior disorder (RBD) is also associated with synucleinopathies and considered as a powerful predictor of PD. Growing evidence suggests the diminished clearanc...

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Bibliographic Details
Main Authors: Xiao-li Si, Lu-yan Gu, Zhe Song, Cheng Zhou, Yi Fang, Chong-yao Jin, Jing-jing Wu, Ting Gao, Tao Guo, Xiao-jun Guan, Xiao-jun Xu, Xin-zhen Yin, Ya-ping Yan, Min-min Zhang, Jia-li Pu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson’s disease
REM sleep behavior disorder
perivascular space
glymphatic system
white matter hyperintensity
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.580853/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2020.580853/full

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