Folate-Equipped Nanolipoplexes Mediated Efficient Gene Transfer into Human Epithelial Cells

Folate-Equipped Nanolipoplexes Mediated Efficient Gene Transfer into Human Epithelial Cells

Since recombinant viral vectors have been associated with serious side effects, such as immunogenicity and oncogenicity, synthetic delivery systems represent a realistic alternative for achieving efficacy in gene therapy. A major challenge for non-viral nanocarriers is the optimization of transgene...

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Bibliographic Details
Main Authors: Tristan Montier, Thierry Benvegnu, Pierre Lehn, Remi Marianowski, Claude Férec, Isabelle Laurent, Tony Le Gall, Loïc Lemiègre, Céline Lainé, Emmanuel Mornet, Nathalie Carmoy
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:International Journal of Molecular Sciences
Subjects:
cystic fibrosis
cationic lipids
neutral lipid nanocomplexes
folic acid
folate receptors
epithelial cells
Online Access:http://www.mdpi.com/1422-0067/14/1/1477

Internet

http://www.mdpi.com/1422-0067/14/1/1477

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