A novel stop codon mutation in exon 5 (c.639G>A) of the cadherin-1 gene in a Vietnamese man with hereditary diffuse gastric cancer: a case report

A novel stop codon mutation in exon 5 (c.639G>A) of the cadherin-1 gene in a Vietnamese man with hereditary diffuse gastric cancer: a case report

Abstract Background Germline pathogenic variants in the cadherin-1 (CDH1) gene cause a predisposition to hereditary diffuse gastric cancer (HDGC). We report an HDGC case in Vietnam and identify a novel mutation in the CDH1 gene. Case presentation A 28-year-old Vietnamese man was diagnosed with HDGC...

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Bibliographic Details
Main Authors: Dzung Ngoc Thi Dang, Huong Thanh Thi Nguyen, Hoa Dieu Ngo, Bac Manh Tran, Anh Duc Vu, Huy Quang Dang, Van Thanh Ta
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Medical Case Reports
Subjects:
Case report
Cadherin-1
Hereditary diffuse gastric cancer
C.639G>A
Online Access:https://doi.org/10.1186/s13256-021-02837-y

Internet

https://doi.org/10.1186/s13256-021-02837-y

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