Frequency and pattern of heteroplasmy in the complete human mitochondrial genome.

Determining the levels of human mitochondrial heteroplasmy is of utmost importance in several fields. In spite of this, there are currently few published works that have focused on this issue. In order to increase the knowledge of mitochondrial DNA (mtDNA) heteroplasmy, the main goal of this work is...

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Bibliographic Details
Main Authors: Amanda Ramos, Cristina Santos, Ligia Mateiu, Maria del Mar Gonzalez, Luis Alvarez, Luisa Azevedo, António Amorim, Maria Pilar Aluja
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3788774?pdf=render