Muscle‐restricted nuclear receptor interaction protein knockout causes motor neuron degeneration through down‐regulation of myogenin at the neuromuscular junction

Muscle‐restricted nuclear receptor interaction protein knockout causes motor neuron degeneration through down‐regulation of myogenin at the neuromuscular junction

Abstract Background Nuclear receptor interaction protein (NRIP) is a calcium/calmodulin (CaM) binding protein. Nuclear receptor interaction protein interacts with CaM to activate calcineurin and CaMKII signalling. The conventional NRIP knockout mice (global knockout) showed muscular abnormality with...

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Bibliographic Details
Main Authors: Hsin‐Hsiung Chen, Li‐Kai Tsai, Kuan‐Yu Liao, Tung‐Chien Wu, Yun‐Hsin Huang, Yuan‐Chun Huang, Szu‐Wei Chang, Pei‐Yu Wang, Yeou‐Ping Tsao, Show‐Li Chen
Format: Article
Language:English
Published: Wiley 2018-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
NRIP
Motor neuron
Neuromuscular junction
Myogenin
Online Access:https://doi.org/10.1002/jcsm.12299

Internet

https://doi.org/10.1002/jcsm.12299

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