High throughput surface plasmon resonance imaging method for clinical detection of presence and strength of binding of IgM, IgG and IgA antibodies against SARS-CoV-2 during CoViD-19 infection

High throughput surface plasmon resonance imaging method for clinical detection of presence and strength of binding of IgM, IgG and IgA antibodies against SARS-CoV-2 during CoViD-19 infection

Surface Plasmon Resonance imaging (SPRi) was used to determine the presence and strength of binding of IgG, IgM and IgA against the Receptor Binding Domain (RBD) of SARS-CoV-2 in sera of 102 CoViD-19 and non-CoViD-19 patients. The SPRi assay simultaneously measures the antibody isotype levels and th...

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Bibliographic Details
Main Authors: Richard B.M. Schasfoort, Jos van Weperen, Margot van Amsterdam, Judicaël Parisot, Jan Hendriks, Michelle Koerselman, Marcel Karperien, Anouk Mentink, Martin Bennink, Hans Krabbe, Leon WMM Terstappen, A.H. Leontine Mulder
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:MethodsX
Subjects:
Clinical antibody detection generated by SARS-CoV-2 with high throughput Surface Plasmon Resonance imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016121002259

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http://www.sciencedirect.com/science/article/pii/S2215016121002259

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