Association of TGF-β1 and TNF-α genes polymorphisms with the kidney scars forming risk in children with vesicoureteral reflux

Association of TGF-β1 and TNF-α genes polymorphisms with the kidney scars forming risk in children with vesicoureteral reflux

Matrix accumulation in the tissue is the main pathological feature of fibrosis. TGF-β1 stimulates the production of extracellular matrix protein and induces fibrosis in different tissues. TNF-α is a proinflammatory cytokine produced in the kidneys by proximal tubular cells, mesenchymal c...

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Bibliographic Details
Main Authors: Jugović Dragana, Miljković Predrag, Jevtović-Stoimenov Tatjana, Despotović Milena, Madić Višnja, Milićević Aleksandar, Vukelić-Nikolić Marija, Vasiljević Perica
Format: Article
Language:English
Published: Serbian Genetics Society 2019-01-01
Series:Genetika
Subjects:
gene polymorphism
PCR
TNF-α
TGF-β1
VUR
kidney scars
Online Access:http://www.doiserbia.nb.rs/img/doi/0534-0012/2019/0534-00121902701J.pdf

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http://www.doiserbia.nb.rs/img/doi/0534-0012/2019/0534-00121902701J.pdf

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