NF-kB-dependent activation of STAT3 by H. pylori is suppressed by TFF1

NF-kB-dependent activation of STAT3 by H. pylori is suppressed by TFF1

Abstract Background H. pylori infection is the main risk factor for gastric cancer. In this study, we investigated H. pylori-mediated activation of STAT3 and NF-κB in gastric cancer, using in vitro and in vivo models. Methods To investigate the activation of NF-κB and STAT3 by H. pylori strains we u...

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Bibliographic Details
Main Authors: Mohammed Soutto, Nadeem Bhat, Shayan Khalafi, Shoumin Zhu, Julio Poveda, Monica Garcia-Buitrago, Alexander Zaika, Wael El-Rifai
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cancer Cell International
Subjects:
TFF1
Helicobacter pylori
NFκB
STAT3
Gastric cancer
H. pylori-induced
Online Access:https://doi.org/10.1186/s12935-021-02140-2

Internet

https://doi.org/10.1186/s12935-021-02140-2

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