NF-kB-dependent activation of STAT3 by H. pylori is suppressed by TFF1
Abstract Background H. pylori infection is the main risk factor for gastric cancer. In this study, we investigated H. pylori-mediated activation of STAT3 and NF-κB in gastric cancer, using in vitro and in vivo models. Methods To investigate the activation of NF-κB and STAT3 by H. pylori strains we u...
Main Authors: | Mohammed Soutto, Nadeem Bhat, Shayan Khalafi, Shoumin Zhu, Julio Poveda, Monica Garcia-Buitrago, Alexander Zaika, Wael El-Rifai |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-08-01
|
Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-021-02140-2 |
Similar Items
-
TFF1 Induces Aggregation and Reduces Motility of <i>Helicobacter pylori</i>
by: Daniela Eletto, et al.
Published: (2021-02-01) -
The Interaction of <i>Helicobacter pylori</i> with TFF1 and Its Role in Mediating the Tropism of the Bacteria Within the Stomach
by: Marguerite Clyne, et al.
Published: (2019-09-01) -
Aberrant JAK/STAT Signaling Suppresses TFF1 and TFF2 through Epigenetic Silencing of GATA6 in Gastric Cancer
by: Cheng-Shyong Wu, et al.
Published: (2016-09-01) -
IVTH BRAZILIAN CONSENSUS CONFERENCE ON HELICOBACTER PYLORI INFECTION
by: Luiz Gonzaga Vaz COELHO, et al.
Published: (2018-04-01) -
Helicobacter pylori eradication: Current aspects
by: V V Tsukanov, et al.
Published: (2013-02-01)