Role of the IgM Fc Receptor in Immunity and Tolerance

Immunoglobulin (Ig) M is the first antibody isotype to appear during evolution, ontogeny and immune responses. IgM not only serves as the first line of host defense against infections but also plays an important role in immune regulation and immunological tolerance. For many years, IgM is thought to...

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Bibliographic Details
Main Authors: Jun Liu, Ying Wang, Ermeng Xiong, Rongjian Hong, Qing Lu, Hiroshi Ohno, Ji-Yang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
IgM
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00529/full