Analog Signaling With the “Digital” Molecular Switch CaMKII

Molecular switches, such as the protein kinase CaMKII, play a fundamental role in cell signaling by decoding inputs into either high or low states of activity; because the high activation state can be turned on and persist after the input ceases, these switches have earned a reputation as “digital.”...

Full description

Bibliographic Details
Main Author: Stephen E. Clarke
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncom.2018.00092/full