Guidelines for benchmarking of optimization-based approaches for fitting mathematical models
Abstract Insufficient performance of optimization-based approaches for the fitting of mathematical models is still a major bottleneck in systems biology. In this article, the reasons and methodological challenges are summarized as well as their impact in benchmark studies. Important aspects for achi...
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| Format: | Article |
| Language: | English |
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BMC
2019-12-01
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| Series: | Genome Biology |
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| Online Access: | https://doi.org/10.1186/s13059-019-1887-9 |