Clinical Genotyping of Non–Small Cell Lung Cancers Using Targeted Next-Generation Sequencing: Utility of Identifying Rare and Co-mutations in Oncogenic Driver Genes
Detection of somatic mutations in non–small cell lung cancers (NSCLCs), especially adenocarcinomas, is important for directing patient care when targeted therapy is available. Here, we present our experience with genotyping NSCLC using the Ion Torrent Personal Genome Machine (PGM) and the AmpliSeq C...
Main Authors: | Laura J. Tafe, Kirsten J. Pierce, Jason D. Peterson, Francine de Abreu, Vincent A. Memoli, Candice C. Black, Jason R. Pettus, Jonathan D. Marotti, Edward J. Gutmann, Xiaoying Liu, Keisuke Shirai, Konstantin H. Dragnev, Christopher I. Amos, Gregory J. Tsongalis |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-09-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558616301282 |
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