Origins of Combination Therapy for Tuberculosis: Lessons for Future Antimicrobial Development and Application

Tuberculosis is a global health problem that causes the death of approximately 1.5 million people worldwide each year (WHO, p. 1–126, Global Tuberculosis Report, 2015). Treatment of drug-susceptible tuberculosis requires combination antimicrobial therapy with a minimum of four antimicrobial agents a...

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Bibliographic Details
Main Authors: Christopher A. Kerantzas, William R. Jacobs, Eric J. Rubin, R. John Collier
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e01586-16