Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination.

Tracking and isolating live cells based on their proliferative history in live animals remains a technical challenge in animal studies. We have designed a genetic marking system for tracking the proliferative frequency and history of lymphocytes during their development and homeostatic maintenance....

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Bibliographic Details
Main Authors: Baojun Zhang, Meifang Dai, Qi-Jing Li, Yuan Zhuang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3814321?pdf=render