Early growth inhibition is followed by increased metastatic disease with vitamin D (calcitriol) treatment in the TRAMP model of prostate cancer.

Early growth inhibition is followed by increased metastatic disease with vitamin D (calcitriol) treatment in the TRAMP model of prostate cancer.

The active metabolite of vitamin D3, 1,25-dihydroxyvitamin D3 (calcitriol) has antiproliferative effects in non-aggressive prostate cancer, however, its effects in more aggressive model systems are still unclear. In these studies, effects of calcitriol and a less-calcemic vitamin D analog, QW-1624F2...

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Bibliographic Details
Main Authors: Adebusola Alagbala Ajibade, Jason S Kirk, Ellen Karasik, Bryan Gillard, Michael T Moser, Candace S Johnson, Donald L Trump, Barbara A Foster
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3935875?pdf=render

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http://europepmc.org/articles/PMC3935875?pdf=render

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