KILchip v1.0: A Novel Plasmodium falciparum Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization

KILchip v1.0: A Novel Plasmodium falciparum Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization

Passive transfer studies in humans clearly demonstrated the protective role of IgG antibodies against malaria. Identifying the precise parasite antigens that mediate immunity is essential for vaccine design, but has proved difficult. Completion of the Plasmodium falciparum genome revealed thousands...

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Bibliographic Details
Main Authors: Gathoni Kamuyu, James Tuju, Rinter Kimathi, Kennedy Mwai, James Mburu, Nelson Kibinge, Marisa Chong Kwan, Sam Hawkings, Reuben Yaa, Emily Chepsat, James M. Njunge, Timothy Chege, Fatuma Guleid, Micha Rosenkranz, Christopher K. Kariuki, Roland Frank, Samson M. Kinyanjui, Linda M. Murungi, Philip Bejon, Anna Färnert, Kevin K. A. Tetteh, James G. Beeson, David J. Conway, Kevin Marsh, Julian C. Rayner, Faith H. A. Osier
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
Plasmodium falciparum
merozoite
antibodies
vaccine candidates
protein microarray
bioinformatics
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02866/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02866/full

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