Role of Fc in Antibody-Mediated Protection from Ricin Toxin

Role of Fc in Antibody-Mediated Protection from Ricin Toxin

We have studied the role of the antibody (Ab) Fc region in mediating protection from ricin toxicity. We compared the in vitro and in vivo effects of intact Ig and of Fab fragments derived from two different neutralizing Ab preparations, one monoclonal, the other polyclonal. Consistent results were o...

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Bibliographic Details
Main Authors: Seth. H. Pincus, Anushka Das, Kejing Song, Grace A. Maresh, Miriam Corti, Jody Berry
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Toxins
Subjects:
ricin
monoclonal antibody
polyclonal antiserum
Fc region
Fc receptor
Fab
neutralization
in vivo protection
Online Access:http://www.mdpi.com/2072-6651/6/5/1512

Internet

http://www.mdpi.com/2072-6651/6/5/1512

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