Glycomic analysis of human respiratory tract tissues and correlation with influenza virus infection.

Glycomic analysis of human respiratory tract tissues and correlation with influenza virus infection.

The first step in influenza infection of the human respiratory tract is binding of the virus to sialic (Sia) acid terminated receptors. The binding of different strains of virus for the receptor is determined by the α linkage of the sialic acid to galactose and the adjacent glycan structure. In this...

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Main Authors: Trevenan Walther, Rositsa Karamanska, Renee W Y Chan, Michael C W Chan, Nan Jia, Gillian Air, Clark Hopton, Maria P Wong, Anne Dell, J S Malik Peiris, Stuart M Haslam, John M Nicholls
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3597497?pdf=render

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http://europepmc.org/articles/PMC3597497?pdf=render

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