The role of molecular genetic alterations in sensitivity of the adjuvant intravesical therapy for non-muscle invasive bladder cancer

The role of molecular genetic alterations in sensitivity of the adjuvant intravesical therapy for non-muscle invasive bladder cancer

Bladder cancer (BC) is represented by non-muscle-invasive forms at the stage Ta, T1, CIS (NMBC) in 75 % of cases. The gold standard of treatment of NMBC patients is transurethral resection, but its implementation does not always allow the patient to be relieved of the recurrence of the disease. In t...

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Bibliographic Details
Main Authors: D. S. Mikhaylenko, S. A. Sergienko, I. N. Zaborsky, K. N. Saflullin, S. A. Serebryany, N. Yu. Safronova, M. V. Nemtsova, A. D. Kaprin, B. Ya. Alekseev
Format: Article
Language:Russian
Published: ABV-press 2019-01-01
Series:Onkourologiâ
Subjects:
bladder cancer
microsatellite instability
genetic polymorphism
mutational load
bcg therapy
somatic mutation
immunotherapy
gene expression
Online Access:https://oncourology.abvpress.ru/oncur/article/view/894

Internet

https://oncourology.abvpress.ru/oncur/article/view/894

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