Lymphatic Vessels Balance Viral Dissemination and Immune Activation following Cutaneous Viral Infection

Lymphatic Vessels Balance Viral Dissemination and Immune Activation following Cutaneous Viral Infection

Lymphatic vessels lie at the interface between peripheral sites of pathogen entry, adaptive immunity, and the systemic host. Though the paradigm is that their open structure allows for passive flow of infectious particles from peripheral tissues to lymphoid organs, virus applied to skin by scarifica...

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Bibliographic Details
Main Authors: Christopher P. Loo, Nicholas A. Nelson, Ryan S. Lane, Jamie L. Booth, Sofia C. Loprinzi Hardin, Archana Thomas, Mark K. Slifka, Jeffrey C. Nolz, Amanda W. Lund
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
lymphatic vessels
cutaneous infection
vaccinia virus
type I interferons
dissemination
tissue microenvironment
tissue immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717312676

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http://www.sciencedirect.com/science/article/pii/S2211124717312676

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