Alteration of autophagosomal proteins in the brain of multiple system atrophy

Alteration of autophagosomal proteins in the brain of multiple system atrophy

Autophagosomal formation is an initial step for macroautophagy. Similar to the yeast autophagy-related gene 8 (ATG8), mammalian ATG8 is responsible for autophagosomal formation, and categorized into LC3 and GABARAPs/GATE-16. Recent studies have shown that impairment of the autophagy–lysosome system...

Full description

Bibliographic Details
Main Authors: Kunikazu Tanji, Saori Odagiri, Atsushi Maruyama, Fumiaki Mori, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Neurobiology of Disease
Subjects:
Autophagy
GABARAP
GATE-16
Glial cytoplasmic inclusion
LC3
Lysosome
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611200304X

Internet

http://www.sciencedirect.com/science/article/pii/S096999611200304X

Similar Items