Flavonoids-Rich Orthosiphon stamineus Extract as New Candidate for Angiotensin I-Converting Enzyme Inhibition: A Molecular Docking Study

Flavonoids-Rich Orthosiphon stamineus Extract as New Candidate for Angiotensin I-Converting Enzyme Inhibition: A Molecular Docking Study

This study aims to evaluate the in vitro angiotensin-converting enzyme (ACE) inhibition activity of different extracts of Orthosiphon stamineus (OS) leaves and their main flavonoids, namely rosmarinic acid (RA), sinensetin (SIN), eupatorin (EUP) and 3′-hydroxy-5,6,7,4′-tetramethoxyflavone (TMF). Fur...

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Bibliographic Details
Main Authors: Armaghan Shafaei, Md Shamsuddin Sultan Khan, Abdalrahim F. A. Aisha, Amin Malik Shah Abdul Majid, Mohammad Razak Hamdan, Mohd Nizam Mordi, Zhari Ismail
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Molecules
Subjects:
angiotensin-converting enzyme
hypertension
flavonoids
HPLC-UV
molecular ducking study
Online Access:http://www.mdpi.com/1420-3049/21/11/1500

Internet

http://www.mdpi.com/1420-3049/21/11/1500

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