Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol

Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol

A novel lyase activity enzyme is characterized for the first time: HMG-CoA lyase-like1 (er-cHL), which is a close homolog of mitochondrial HMG-CoA lyase (mHL). Initial data show that there are nine mature transcripts for the novel gene HMGCLL1, although none of them has all its exons. The most abund...

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Bibliographic Details
Main Authors: María Arnedo, Sebastián Menao, Beatriz Puisac, María E. Teresa-Rodrigo, María C. Gil-Rodríguez, Eduardo López-Viñas, Paulino Gómez-Puertas, Nuria Casals, César H. Casale, Fausto G. Hegardt, Juan Pié
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Journal of Lipid Research
Subjects:
enzymology
kinetics
liver
lung
brain
ketone bodies
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520431827

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520431827

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