Human primary adipocytes exhibit immune cell function: adipocytes prime inflammation independent of macrophages.

Human primary adipocytes exhibit immune cell function: adipocytes prime inflammation independent of macrophages.

BACKGROUND: Obesity promotes inflammation in adipose tissue (AT) and this is implicated in pathophysiological complications such as insulin resistance, type 2 diabetes and cardiovascular disease. Although based on the classical hypothesis, necrotic AT adipocytes (ATA) in obese state activate AT macr...

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Bibliographic Details
Main Authors: Kees Meijer, Marcel de Vries, Saad Al-Lahham, Marcel Bruinenberg, Desirée Weening, Martijn Dijkstra, Niels Kloosterhuis, Roelof Jan van der Leij, Han van der Want, Bart-Jan Kroesen, Roel Vonk, Farhad Rezaee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3063154?pdf=render

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http://europepmc.org/articles/PMC3063154?pdf=render

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