Fed-batch fermentation of GM-CSF-producing glycoengineered <it>Pichia pastoris </it>under controlled specific growth rate

<p>Abstract</p> <p>Background</p> <p>Yeast expression systems with altered N-glycosylation are now available to produce glycoproteins with homogenous, defined N-glycans. However, data on the behaviour of these strains in high cell density cultivation are scarce.</p&g...

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Bibliographic Details
Main Authors: Haustraete Jurgen, Festjens Nele, Inan Mehmet, Jacobs Pieter P, Van Hecke Annelies, Contreras Roland, Meagher Michael M, Callewaert Nico
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/9/1/93