Fed-batch fermentation of GM-CSF-producing glycoengineered <it>Pichia pastoris </it>under controlled specific growth rate
<p>Abstract</p> <p>Background</p> <p>Yeast expression systems with altered N-glycosylation are now available to produce glycoproteins with homogenous, defined N-glycans. However, data on the behaviour of these strains in high cell density cultivation are scarce.</p&g...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-11-01
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Series: | Microbial Cell Factories |
Online Access: | http://www.microbialcellfactories.com/content/9/1/93 |