Synthetic Lethal Screen Identifies NF-κB as a Target for Combination Therapy with Topotecan for patients with Neuroblastoma

<p>Abstract</p> <p>Background</p> <p>Despite aggressive multimodal treatments the overall survival of patients with high-risk neuroblastoma remains poor. The aim of this study was to identify novel combination chemotherapy to improve survival rate in patients with high-...

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Bibliographic Details
Main Authors: Tsang Patricia S, Cheuk Adam T, Chen Qing-Rong, Song Young K, Badgett Thomas C, Wei Jun S, Khan Javed
Format: Article
Language:English
Published: BMC 2012-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/12/101