Optimal Labeling Dose, Labeling Time, and Magnetic Resonance Imaging Detection Limits of Ultrasmall Superparamagnetic Iron-Oxide Nanoparticle Labeled Mesenchymal Stromal Cells

Background. Regenerative therapy is an emerging treatment modality. To determine migration and retention of implanted cells, it is crucial to develop noninvasive tracking methods. The aim was to determine ex vivo magnetic resonance imaging (MRI) detection limits of ultrasmall superparamagnetic iron-...

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Bibliographic Details
Main Authors: Anders Bruun Mathiasen, Louise Hansen, Tina Friis, Carsten Thomsen, Kishore Bhakoo, Jens Kastrup
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2013/353105