Overexpression of lncRNAs with endogenous lengths and functions using a lncRNA delivery system based on transposon

Overexpression of lncRNAs with endogenous lengths and functions using a lncRNA delivery system based on transposon

Abstract Background Long noncoding RNAs (lncRNAs) play important roles in many physiological and pathological processes, this indicates that lncRNAs can serve as potential targets for gene therapy. Stable expression is a fundamental technology in the study of lncRNAs. The lentivirus is one of the mo...

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Bibliographic Details
Main Authors: Yin Zhang, Yong-Xin Huang, Xin Jin, Jie Chen, Li Peng, Dan-Lan Wang, Yun Li, Xin-Yi Yao, Jian-You Liao, Jie-Hua He, KaiShun Hu, Daning Lu, Yabin Guo, Dong Yin
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Journal of Nanobiotechnology
Subjects:
lncRNA
Non-viral delivery
Ectopic overexpression
Sleeping Beauty transposon
Lentivirus
Online Access:https://doi.org/10.1186/s12951-021-01044-7

Internet

https://doi.org/10.1186/s12951-021-01044-7

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