Biased Signaling of Protease-activated Receptors

In addition to their role in protein degradation and digestion, proteases can also function as hormone-like signaling molecules that regulate vital patho-physiological processes, including inflammation, hemostasis, pain and repair mechanisms. Certain proteases can signal to cells by cleaving proteas...

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Bibliographic Details
Main Authors: Peishen eZhao, Matthew eMetcalf, Nigel William Bunnett
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00067/full