Cancer-associated mesenchymal stem cells aggravate tumor progression

Mesenchymal stem cells (MSCs) have both stemness and multi-modulatory activities on other cells, and the immunosuppressive and tumor-promotive mechanisms have been intensively investigated in cancer. The role of MSCs appears to be revealed in tumor aggravation, and targeting MSCs seems to be a promi...

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Bibliographic Details
Main Author: Chie eKudo-Saito
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00023/full